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ShangHai YiJing Industrial Co,LTD
ShangHai YiJing Industrial Co,LTD
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99% Injectable Polypeptide Hormones Corticotropin CAS 9002-60-2 ACTH For Muscle Building & Collagen Diseases

99% Injectable Polypeptide Hormones Corticotropin CAS 9002-60-2 ACTH For Muscle Building & Collagen Diseases

Brand Name : yijing
Model Number : gclb5t@yccreate.com
Certification : ISO9001
Place of Origin : china
MOQ : 10G
Price : 10USD
Payment Terms : T/T, Western Union, MoneyGram
Supply Ability : 200-300kg per Month
Delivery Time : 3-6 working days
Packaging Details : 1kg/aluminium foil bag or as required
Alias : Corticotropin
Purity : 99
CAS : 9002-60-2
EINECS : 227-712-6
email : gclb5t@yccreate.com
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Muscle Building Polypeptide Hormones 9002-60-2 ACTH Adrendcorticotrophic Hormone

99% Injectable Polypeptide Hormones Corticotropin CAS 9002-60-2 ACTH For Muscle Building & Collagen Diseases

Corticotropin
Alias : Adrendcorticotrophic hormone, ACTH, ACTH 1-39 , acethropan
CAS NO. : 9002-60-2
EINECS 232-659-7
MF : C207H308N56O58S
MW : 4541.07
MS :
Muscle Building Polypeptide Hormones 9002-60-2 ACTH Adrendcorticotrophic Hormone
Purity (HPLC): 99%
Appearance: White or light yellow powder, odorless, moisture, soluble in water, soluble in 70% acetone and 70% ethanol
Grade : Pharmaceutical Grade
Storage: Closed, ?20°C preservation
Usage : Hormone kind medicine, promote the secretion of adrenal cortical hormone, used in active

rheumatism, rheumatoid arthritis, lupus and other collagen diseases. Clinical use of cortisone similar


Product Description:


This product is composed of 39 amino acid residues, species differences only in the 25-33 position, 1-24 bits of the fragment with all the activity, twenty-fourth amino acid after the part only to maintain stability of the whole polypeptide structure. In the solution is highly - Helical structure. By partial hydrolysis of pepsin is still active.
This product is poor efficacy of oral invalid; intramuscular injection; intravenous injection effect is fast, but has a half-life of only 15min, hold time 1-3h.
Adrenocorticotropic hormone, commonly referred to as ACTH and also known as corticotropin, is a polypeptide hormone produced in and secreted by the anterior pituitary gland. It is a key component in the hypothalamic-pituitary-adrenal axis, often produced in response to exogenous biological stress along with corticotropin-releasing hormone (which is also from the hypothalamus.) Its effects include increased production and release of corticosteroids and, as its name suggests, cortisol from the adrenal cortex.
ACTH acts through the stimulation of cell surface ACTH receptors, which are located primarily on adrenocortical cells of the adrenal cortex. This results in the synthesis and secretion of gluco- and mineralo-corticosteroids and androgenic steroids. The ACTH receptor is a seven-membrane-spanning G protein-coupled receptor. Upon ligand binding, the receptor undergoes conformation changes that stimulate the enzyme adenylyl cyclase, which leads to an increase in intracellular cAMP and subsequent activation of protein kinase A. This ultimately results in stimulation of steroidogenesis. Steroidogenesis. Steroidogenesis is the biological process by which steroids are generated from cholesterol and transformed into other steroids. The pathways of steroidogenesis differ between different species, but the pathways of human steroidogenesis are shown in the figure. Products of steroidogenesis include: androgens testosterone estrogens and progesterone corticoids cortisol aldosterone ACTH acts at several key steps to influence the steroidogenic pathway in the adrenal cortex: ACTH stimulates lipoprotein uptake into cortical cells. This increases the bio-availability of cholesterol in the cells of the adrenal cortex. ACTH increases the transport of cholesterol into the mitochondria and activates its hydrolysis. ACTH Stimulates cholesterol side-chain cleavage enzyme, which makes the rate-limiting step in steroidogenesis. This results in the production of pregnenolone



Results Of Analysis Tests
Test Of AnalysisStandard Of AnalysisResults Of Analysis
DescriptionWhite Crystalline PowderWhite Crystalline Powder
IdentificationIR,ULPositive
Assay98.0~100.5%99.7%
Loss On Drying1.0%max(5mm Hg, 100°C)0.2%
Specific Rotation+34°~+40°(C=1, Chloroform)'+36.5°
Chromatographic purityTotal Impurities: 2.0%max<2.0%
Organic volatile impuritiesmeets the requirements.Comforms
Residual solventsEthanol: 5000PPm max310PPm
ConclusionThe specification conform with USP30 standard


Contact me by email gclb5t@yccreate.com


Competitive Advantages:

ShangHai YiJing Industrial Co,LTD is a renowned pharmaceutical manufacturer, specializing in raw steroid powders in Mainland China. It is not only the leading manufacturer of steroids powder and pharmaceutical raw materials in the central area of China but also exports all over the world. All powders are factory directly supplying.
Our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries. Monthly output is over 100kgs. We cherish a great number of loyal customers serving in gym fields, athletes fields , medical institution ,clinics and so on
Top quality products with the most competitive rate. Free samples are available.
Well disguised packing. Fast and secure delivery by DHL, TNT, FedEx, HKEMS, UPS, etc.
Flexible and Untraceable payment terms
Exclusive customer service and 24/7 online timely and helpful After-sale service.


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